Imo, either herb/inscription, mining/jc, or mining/engineering.
You really need the supplying profession for the crafting profession to level it efficiently.
Skinning isn't as profitable as herbalism or mining, since it really only has Leatherworking as a crafting prof. Mining is really the way to go, as the 20 hour cooldown can be rather profitable.
JC isn't that horrible to level if you have mining to support it.
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